The issue with ozone is that it is only present in a certain percentage of the water at any one time. Note that with an ozonator you only need a small amount of residual sanitizer such as chlorine or bromine...
Adding 3+ ozonator units to a spa would have the same effect as constantly adding too much chlorine or bromine. Having so much of an oxidizer like ozone in the water would eat your spa components too... which means your jets, spa cover, anything plastic, pump seals.... and your skin, and you'd have headaches forever just trying to use such an animal.
My favorite combination is an ozonator, with a
Spa Frog and .5ppm bromine or chlorine; which is ideal.